Qualifying charitable donations and loss relief

Hello, I have a question regarding qualifying charitable donations. I understand that if we use the current period loss relief against total profits the qualifying charitable donations become unrelieved a.k.a. we cannot use them for deduction because they are wasted.

What about if we don’t offset current period loss against total profits but we only offset carry back loss relief? Can we still use qualifying charitable donations to deduct total profits?

Thanks in advance.